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Editorial Reviews

Victor Manuelle success has been undeniable since the mid 90's and in the turn of the new century his latest album "Decisión Unámine" was perhaps Manuelle's most admired album since Instinto y Deseo, if not A Pesar de Todo. In addition to the album's success, Manuelle co-hosted the 2006 Latin Grammys and won a 2007 Premio Lo Nuestro award for Best Salsa Artist of the year. Accompanied by his recent acclamations, Victor Manuelle now gracefully delivers his newest production "Yo Mismo" which in English translates to "Myself": rightfully titled due the fact that Victor Manuelle is the producer and writer of all the songs as well as he independently owns the production via his own label, Kiyavi records. Aside from Luis Fonsi, the production includes compositions from highly distinguished composers Amaury Gutierrez and Jorge Piloto, Claudia Brant and Sin Banderas' Noel. "Yo Mismo" includes two ballads, continuing the tradition that has made Victor Manuelle the beloved tropical icon he is today. The debut single "Mirame" is a fusion of salsa with flamenco that distinguishes it from anything ever heard before, injecting us with modern fresh sounds that are destined to appeal to a crossover market.

Yo Mismo

Bioscience is a vast puzzle, which sounds like fun—until you remember that puzzles can be frustrating, especially if they’re missing crucial pieces. Fortunately, as this issue of GEN indicates, some of bioscience’s missing pieces are falling into place. Piece one: The tissue-level patterns formed by cells with disparate gene expression profiles. (These patterns, which influence health, are emerging because single-cell technology is being combined with spatial transcriptomics.) Piece two: A smooth Design-Build-Test-Learn (DBTL) cycle in synthetic biology. (DBTL still isn’t turning as freely as it might, but with new DNA-writing technology, more RPMs are expected.) Piece three: CAR T cells that could help more than a minority of cancer patients. (Such cells may be built if allogeneic approaches are used, or if genetic engineering is used to install ancillary immune signals.) So, if you want to solve bioscience puzzles—including those related to outsourcing and bringing NGS to bear in biomanufacturing—read our September issue.

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